Table 4 Possible gene targets and TFs found from the TRANSFAC database for top binding motifs from Table 3
From: Insights gained from the reverse engineering of gene networks in keloid fibroblasts
Binding Motif | Possible gene targets | Possible TFs |
|---|---|---|
CCACACA | - | - |
GGGGCTC | ADA (adenosine deaminase) | SP1 |
GTCCCG | EGFR (EGF receptor) | - |
| Â | ATF2 (activating transcription factor 2) | SP1 |
| Â | CCNE1 (cyclin E1) | E2F-1 |
| Â | MET (hepatocyte growth factor receptor) | PAX-3 |