Table 2 Model Values for Key Indices and Variables in Control and LVDD Cases
From: Modeling left ventricular diastolic dysfunction: classification and key indicators
Parameter | Control | Impaired Relaxation | Restrictive Filling | Pseudo-Normalization | ||||
|---|---|---|---|---|---|---|---|---|
e LV,SPT (t) | normal | normal | altered | altered | normal | normal | altered | altered |
Contractility | normal | increased | normal | increased | normal | increased | normal | increased |
λ DAP =λ DAM (1/ml) | 0.05 | 0.05 | 0.05 | 0.05 | 0.1 | 0.1 | 0.1 | 0.1 |
λ LV (1/ml) | 0.025 | 0.025 | 0.025 | 0.025 | 0.05 | 0.05 | 0.05 | 0.05 |
E LV,ES (mmHg/ml) | 3.5 | 5.6 | 3.5 | 5.6 | 3.5 | 5.6 | 3.5 | 5.6 |
LVEDP (mmHg) | 10.5 | 9.5 | 16.0 | 17.0 | 23.3 | 21.4 | 25.0 | 25.0 |
MSAP (mmHg) mHg)(mmHg) | 96.6 | 98.4 | 91.5 | 91.3 | 89.0 | 90.6 | 84.9 | 85.3 |
CVP (mmHg) | 2.4 | 2.6 | 1.4 | 1.4 | 0.2 | 0.6 | -0.6 | -0.6 |
HR (beats/min) | 55.2 | 53.9 | 60.2 | 60.6 | 63.8 | 61.4 | 68.2 | 68.1 |
CO (l/min) | 4.9 | 5.2 | 3.9 | 3.9 | 3.5 | 3.9 | 3.0 | 3.0 |
LVSV (ml) | 89.4 | 96.0 | 64.7 | 63.9 | 55.3 | 62.7 | 43.5 | 44.1 |
LVEF | 0.72 | 1.4 | 0.68 | 0.76 | 0.65 | 0.76 | 0.63 | 0.72 |
LVET (sec) | 0.28 | 0.31 | 0.26 | 0.27 | 0.29 | 0.31 | 0.27 | 0.28 |
RVSV (ml) | 89.1 | 95.8 | 64.5 | 63.7 | 54.5 | 61.9 | 43.3 | 43.7 |
RVEF | 0.62 | 0.81 | 0.49 | 0.48 | 0.44 | 0.47 | 0.37 | 0.36 |
RVET (sec) | 0.38 | 0.37 | 0.33 | 0.33 | 0.27 | 0.30 | 0.22 | 0.22 |
P AO2 (mmHg) | 105.0 | 104.3 | 106.5 | 106.6 | 108.1 | 106.2 | 108.9 | 108.5 |
P ACO2 (mmHg) | 39.3 | 39.6 | 38.0 | 37.7 | 37.2 | 37.5 | 36.3 | 36.3 |
P TO2 (mmHg) | 42.5 | 43.4 | 37.2 | 36.9 | 33.5 | 35.8 | 29.5 | 29.5 |
P TCO2 (mmHg) | 45.4 | 45.2 | 46.8 | 46.9 | 47.8 | 47.2 | 48.4 | 48.4 |
P BO2 (mmHg) | 37.4 | 37.4 | 37.2 | 37.2 | 36.9 | 37.2 | 36.2 | 36.3 |
P BCO2 (mmHg) | 45.3 | 45.2 | 45.8 | 45.9 | 46.2 | 46.1 | 46.2 | 46.2 |
A-V O2 (T) | 4.4% | 4.4% | 5.9% | 6.0% | 7.1% | 6.2% | 9.0% | 8.9% |
A-V CO2 (T) | -1.9% | -1.9% | -2.4% | -2.4% | -2.7% | -2.5% | -3.1% | -3.1% |
A-V O2 (B) | 5.1% | 5.1% | 5.5% | 5.5% | 5.9% | 5.6% | 6.2% | 6.2% |
A-V CO2 (B) | -0.4% | -0.4% | -0.8% | -0.8% | -0.9% | -0.8% | -1.1% | -1.1% |
F HRv | 0.54 | 0.54 | 0.51 | 0.51 | 0.50 | 0.51 | 0.47 | 0.39 |
F HRs | 0.28 | 0.27 | 0.33 | 0.33 | 0.35 | 0.34 | 0.39 | 0.39 |
F con | 0.40 | 0.38 | 0.45 | 0.46 | 0.49 | 0.47 | 0.53 | 0.53 |
F vaso | 0.54 | 0.51 | 0.62 | 0.62 | 0.64 | 0.62 | 0.70 | 0.69 |
F b | 0.41 | 0.41 | 0.39 | 0.39 | 0.38 | 0.38 | 0.36 | 0.36 |
F c | 0.17 | 0.17 | 0.16 | 0.16 | 0.15 | 0.16 | 0.14 | 0.14 |
F cc | 0.53 | 0.53 | 0.54 | 0.54 | 0.55 | 0.55 | 0.55 | 0.55 |