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Table 2 Metabolic and cellular organization differences between normal and cancer cells [34]

From: Cancer as a dynamical phase transition

Properties

Normal Cells

Cancer Cells

Metabolic

Oxidative phosphorylation: high entropic state

Glycolysis: low entropy state

Cellular

High degree of synchrony in cell cycle

Low degree of synchrony in cell cycle

Phenotype

Homogeneous

Heterogeneous

Motility

Low

High, especially in metastatic cancer

Tissue

High degree of spatial order

Spatial disorder