Figure 5

Optimal control. Numerical studies of optimal control strategies and solutions (A = 1 or $1555, B = 1 or $3000, E = 1/2, F = 1/2): (a) the optimal treatment rates for the baseline model when admission of colonized and infectious patients is present or absent (solid and dashed traces, respectively): (b) the number of infectious patients corresponding to the optimal treatment rates: (c) the optimal treatment rates for patients with and without antibiotic exposure when admission of colonized or infectious patients is present or absent (solid trace=without antibiotic exposure but with admission of colonized or infectious patients, dotted trace=with antibiotic exposure and admission of colonized or infectious patients, dashed trace=without antibiotic exposure and admission of colonized or infectious patients, dashed-dotted trace=with antibiotic exposure but without admission of colonized or infectious patients): (d) the number of infectious patients corresponding to the optimal treatment rates (lines are defined in (c)).