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Table 1 List of parameters for MRSA transmission in hospital settings

From: Modeling methicillin-resistant Staphylococcus aureus in hospitals: Transmission dynamics, antibiotic usage and its history

Description Symbol Value References
Total number of patients N p 600  
Total number of HCWs N h 150  
(Patients: HCWs = 3:1)    [19]
Probability that a person is colonized by MRSA at admission λ c 0.04 [24]
Probability that a person is infected with MRSA at admission λ i 0.001 [25]
Average length of stay of an uncolonized patient (days) 1/γ u 5 [24]
Average length of stay of a colonized patient (days) 1/κ 7 [20]
Probability of becoming infectious m 1 0.3 [23]
Probability of decolonization m 2 0.01 estimated
Rate of progression from colonization to infection ϕ m 1 κ  
Rate of decolonization ω m 2 κ  
Discharge rate of colonized patients γ c (1 − m1m2)κ  
(including death from other causes)    
Average duration of treatment of an infected patient (days) 1/τ 14 [1]
Probability of a successful treatment ρ 0.6 [26]
Death rate of an infected patient γ i (1 − ρ)τ  
(from both disease-related and other causes)    
Total number of contacts that a patient requires per day a 8 [19]
Probability of colonization after a contact with a HCW b p 0.01 [27]
Probability of contamination after a contact with a colonized patient b hc 0.15 [27]
Probability of contamination after a contact with an infected patient b hi 0.30 estimated
Average duration of contamination (days) 1/μ 1/24 [27]
  1. *Note that the probability of decolonization of a colonized patient is estimated by the normal time require for nasal MRSA to revert to the usual MSSA (methicillin-sensitive Staphylococcus aureus) which is approximately 30 days[28]. Hence, we here estimate the probability of decolonization by probability that a patient stays longer than thirty days[29].