Table 3 Functional annotation of the top ten genes selected using Euclidean distance
Affy ID | Gene symbol | Entrez gene ID | Gene type | GO processes | Oncology | KEGG pathways |
|---|---|---|---|---|---|---|
201893_x_at, 211896_s_at, 211813_x_at | DCN | 1634 | Protein coding | Cell growth | Colon Carcinoma, Breast Cancer | (TGF-beta signaling pathway) KEGG ID: [hsa04350] |
202992_at | C7 | 730 | Protein coding | Immune response | Hepatoma cell lined | Immune System, organism-specific biosystem REACTOME ID: [REACT_6900] |
201918_at | SLC25A36, | 55186, | Protein coding | Â | Â | Â |
204319_s_at | Rgs10, | 6001 | Protein coding | Â | Â | G alpha (i) signalling events, organism-specific biosystem REACTOME ID: [REACT_19231] |
211368_s_at | CASP1 | 834 | Protein coding | plays a central role in the execution-phase of cell apoptosis. | Colorectal cancer | Immune System, organism-specific biosystem REACTOME ID: [REACT_6900] |
218589_at | LPAR6 | 10161 | Â | The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. | Â | G alpha (q) signalling events, organism-specific biosystem REACTOME ID: [REACT_18283] |
212509_s_at | mxra7 | 439921 | Protein coding | Â | Â | Â |
201278_at | DAB2 | 1601 | Protein coding | The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. | Prostate cancer, breast cancer | Endocytosis, organism-specific biosystem KEGG ID: [hsa04144] |