Detection of biomarkers for Hepatocellular Carcinoma using a hybrid univariate gene selection methods

Table 5 Functional annotation of the top ten genes selected using the hybrid technique

Affy ID	Gene symbol	Entrez gene ID	Gene type	GO processes	Oncology	KEGG pathways
208949_s_at	LGALS3	3958	Protein coding	Immune response, cell adhesion, T-cell regulation	Skin cancer, Breast cancer, Colon cancer, Lung cancer, Cervical cancer, Colorectal cancer, Bladder cancer, Thyroid cancer, Pancreatic cancer, prostate cancer, HCC	Immune System, organism-specific biosystem REACTOME ID: [REACT_6900]
202157_s_at	CELF2	10659	Protein coding	Regulation of heart contraction	Breast cancer, Colon Cancer	mRNA processing, organism-specific biosystem WikiPathways ID: [WP411]
209606_at	CYTIP		Protein coding	Regulation of cell adhesion
202992_at	C7	730	Protein coding	Immune response	Hepatoma cell lined	Immune System, organism-specific biosystem REACTOME ID: [REACT_6900]
211813_x_at, 211896_s_at, 201893_x_at	DCN	1634	Protein coding	Cell growth	Colon Carcinoma, Breast Cancer	(TGF-beta signaling pathway) KEGG ID: [hsa04350]
211919_s_at	CXCR4	7852	Protein coding	inflammatory response, response to viral	HCC, prostate cancer, kidney cancer, Breast cancer, Lung cancer, bladder cancer, Pancreatic cancer, Colorectal cancer, Thyroide cancer, Qastric cancer	CXCR4-mediated signaling events, organism-specific biosystem Pathway Interaction Database ID: [cxcr4_pathway]
214247_s_at	DKK3				Lung cancer, prostate cancer, breast cancer, Head and neck cell carcinoma
201137_s_at	HLA-DPB1				hepatitis C virus (HCV).

ISSN: 1742-4682