Figure 1

Schematic concept of the model. Glucose is given to the system at a constant production rate mainly by the liver. Elevated blood glucose levels lead to immediate release of stored insulin and an enhanced insulin provision. Also, glucose influences the transition rate between phases G1 and S of the cell cycle. Insulin regulates the uptake of glucose in target cells. The molecules are stored in packets with different release thresholds. These packets can be redistributed within the storage.