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Fig. 5 | Theoretical Biology and Medical Modelling

Fig. 5

From: Fanconi anemia cells with unrepaired DNA damage activate components of the checkpoint recovery process

Fig. 5

FA cells have a gene expression pattern compatible with checkpoint resolution despite DNA damage. Gene expression analysis of the genes belonging to the G2 transcriptional program did not show differences in the expression of these genes despite MMC treatment. Cyclin A2 (a), Cyclin B1 (b), WIP1 (c), FOXM1 (d) and PLK1 (e) (n = 3 independent experiments). No statistically significant differences were found in the gene expression patterns among groups

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