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Table 2 Corrected waiting times for single nucleotide substitutions, and strings of 2–8 nucleotides

From: The waiting time problem in a model hominin population

String Length Average number of instances before fixation Average waiting time to 1st instance (yrs) Average waiting time to effective instance (yrs) Average duration of amplification stage (yrs) Total average waiting time (yrs) 95 % confidence intervals for total average waiting time (yrs)
1 27.4 1.89 × 105 1.52 × 106 1.65 × 104 1.53 × 106 4.03 × 105
2 15.0 2.79 × 107 8.40 × 107 1.72 × 104 8.41 × 107 2.01 × 107
3 6.8 2.20 × 108 3.76 × 108 1.73 × 104 3.76 × 108 6.98 × 107
4 12.6 8.30 × 108 1.22 × 109 1.93 × 104 1.22 × 109 1.72 × 108
5 9.0 1.70 × 109 2.31 × 109 1.44 × 104 2.31 × 109 4.98 × 108
6 8.2 3.16 × 109 4.24 × 109 1.62 × 104 4.24 × 109 1.02 × 109
7 6.4 5.52 × 109 8.59 × 109 1.71 × 104 8.59 × 109 2.16 × 109
8 9.3 1.11 × 1010 1.85 × 1010 1.69 × 104 1.85 × 1010 7.25 × 109
  1. Each value is the mean of 25 replicates. The population (10,000) and beneficial fitness effect (10 %) were held constant. The mutation rate was adjusted based on number of nucleotides in the string. For single point mutations (string length of one), numerous instances accumulated simultaneously in the population – such that many were superfluous to waiting time, resulting in extra instances arising prior to fixation