Fig. 3

State transitions leading to a fixed point attractor corresponding to pre-Sertoli or to pre-granulosa cells. The state of the nodes over time was simulated starting from an activated UGR node (1). White and black cells represent inactive or active nodes respectively. The fixed point attractor toward pre-Sertoli is given by activation of SRY node (a). The point attractor is in agreement with experimental observations after six time steps, whereas the fixed point attractor toward granulosa is given by absence of SRY and activated UGR+WNT4 nodes (b). The point attractor is in agreement with experimental observations after three time steps