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Table 1 State of hormonal receptors in several cell lines used as molecular markers for breast cancer diagnosis

From: Toward precision medicine of breast cancer

Cell line Histological subtype ER/PRa HER2b EGFRc CK5-6d
MCF10A Control 0 0-1+ 2+ +
MCF-7 LAe 6 0-1+ 1+ -
T-47D LA >0 2+ - -
ZR-75-1 LA 3-4 2+ 1+ -
BT-474 LBf 0/8 3+ 1+ -
BT-20 TNg 0 0-1+ 2+ -
MB-231 TN 0 0-1+ 1+ -
MB-468 TN 0 0 3+ -
  1. a ER/PR Estrogen/Progesterone receptor, b HER2 Human epidermal growth factor receptor; c EGFR epidermal growth factor, d CK5-6 Cytokeratin 5/6; e LA luminal A, f LB Luminal B, g TN triple-negative
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Theoretical Biology and Medical Modelling

ISSN: 1742-4682