Toward precision medicine of breast cancer

Table 1 State of hormonal receptors in several cell lines used as molecular markers for breast cancer diagnosis

Cell line	Histological subtype	ER/PR^a	HER2^b	EGFR^c	CK5-6^d
MCF10A	Control	0	0-1+	2+	+
MCF-7	LA^e	6	0-1+	1+	-
T-47D	LA	>0	2+	-	-
ZR-75-1	LA	3-4	2+	1+	-
BT-474	LB^f	0/8	3+	1+	-
BT-20	TN^g	0	0-1+	2+	-
MB-231	TN	0	0-1+	1+	-
MB-468	TN	0	0	3+	-

^a ER/PR Estrogen/Progesterone receptor, ^b HER2 Human epidermal growth factor receptor; ^c EGFR epidermal growth factor, ^d CK5-6 Cytokeratin 5/6; ^e LA luminal A, ^f LB Luminal B, ^g TN triple-negative

ISSN: 1742-4682