From: A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies
Model parameters | ||||
---|---|---|---|---|
Parameter | Description | Unit | Value | Reference |
| Duration of G 1 phase | h | 20 | [35,44] |
T S | Duration of S phase | h | 10 | [35,44] |
| Duration of G 2 M phase | h | 3 | [35,44] |
| Duration of G 0 phase | h | 5 | Estimated |
T Apoptosis | Duration of the apoptotic phase | h | 5 | Estimated |
C max | Oxygen in blood | mlO 2 | 10-2 | Estimated |
α φ | Oxygen consumption in phase φ | mlO 2 s -1 | 5 – 10 × 10-15 | Estimated |
Th o | Hypoxia threshold | cell -1 | 5 × 10-15 | Estimated |
Th t | Overpopulation threshold | cell | 2000 | Estimated |
R φ | Cell Radio-sensitivity in phase φ | Gy -1 | 0.2 – 2 | [41-43] |
k | Media permeability | m 2 | 0.2 | Estimated |