Figure 5

Model parameters in response to changes of lactate dehydrogenase activity (V _LDH ). A. [Ca²⁺]_c at different glucose levels. Low glucose level was 7 mM, medium was 9 mM and high was 20 mM; B. Dependence of Ψ_m, J_pyr and J_LDH at a medium glucose concentration ([Glu] = 9 mM). Arrow corresponds to V_LDH (Equation 3) for basal level of coefficient (Table 3). All other parameters were set as in Figure 2.