Fig. 2
From: Computational modeling of the effects of autophagy on amyloid-β peptide levels
The basal steady-state Aβ concentrations and fluxes. CS3 and CES3 represent the concentrations of intracellular (IC) and extracellular (EC) Aβ, respectively. Fgen, Fseq, and Fnap denote the Aβ generation, sequestration (the first step of autophagic degradation, i.e., autophagosome formation), and non-autophagic degradation fluxes, respectively; Fsec and Fclr the secretion (from the IC to the EC space) and Aβ clearance (in the EC space) fluxes, respectively