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Research
A large epidemic of cholera, caused by Vibrio cholerae, serotype Ogawa, has been ongoing in Yemen, 2017. To improve the situation awareness, the present study aimed to forecast the cholera epidemic, explicitly ad...
Theoretical Biology and Medical Modelling 2017 14:14
Published on: 26 July 2017
Research
Herpes Simplex Virus Type 2 (HSV-2) is one of the most common sexually transmitted diseases. Although there is still no licensed vaccine for HSV-2, a theoretical investigation of the potential effects of a vac...
Theoretical Biology and Medical Modelling 2017 14:13
Published on: 17 July 2017
Research
Factors that participate in the biological changes associated with a placebo are not completely understood. Natural evolution, mean regression, concomitant procedures and other non specific effects are well-kn...
Theoretical Biology and Medical Modelling 2017 14:12
Published on: 2 June 2017
Research
With up to 240 million people chronically infected with hepatitis B worldwide, including an estimated 2 million in the United States, widespread screening is needed to link the infected to care and decrease th...
Theoretical Biology and Medical Modelling 2017 14:11
Published on: 18 May 2017
Research
The heterogeneity of response to treatment in patients with glioblastoma multiforme suggests that the optimal therapeutic approach incorporates an individualized assessment of expected lesion progression. In t...
Theoretical Biology and Medical Modelling 2017 14:10
Published on: 2 May 2017
Research
The host range of human immunodeficiency virus (HIV) is quite narrow. Therefore, analyzing HIV-1 pathogenesis in vivo has been limited owing to lack of appropriate animal model systems. To overcome this, chime...
Theoretical Biology and Medical Modelling 2017 14:9
Published on: 21 April 2017
Research
When administering vancomycin hydrochloride (VCM), the initial dose is adjusted to ensure that the steady-state trough value (Css-trough) remains within the effective concentration range. However, the Css-trou...
Theoretical Biology and Medical Modelling 2017 14:8
Published on: 8 April 2017
Research
A deterministic model is developed for the spatial spread of an epidemic disease in a geographical setting. The disease is borne by vectors to
Theoretical Biology and Medical Modelling 2017 14:7
Published on: 27 March 2017
Research
Drug-induced resistance is one the major obstacles that may lead to therapeutic failure during cancer treatment. Different genetic alterations occur when tumor cells divide. Among new generations of tumor cell...
Theoretical Biology and Medical Modelling 2017 14:6
Published on: 21 March 2017
Research
Arteriovenous fistula (AVF) maturation failure remains a major cause of morbidity and mortality in hemodialysis patients. The two major etiologies of AVF maturation failure are early neointimal hyperplasia dev...
Theoretical Biology and Medical Modelling 2017 14:5
Published on: 20 March 2017
Research
Susceptible barcode recognition plays an important role in the diagnosis and treatment of complex diseases. Numerous approaches have been proposed to identify risky barcodes involved in the progress of complex...
Theoretical Biology and Medical Modelling 2017 14:4
Published on: 1 February 2017
Research
The transmission dynamics of Tuberculosis (TB) involve complex epidemiological and socio-economical interactions between individuals living in highly distinct regional conditions. The level of exogenous reinfe...
Theoretical Biology and Medical Modelling 2017 14:3
Published on: 28 January 2017
Research
Urine production in the kidney is generally thought to be an energy-intensive process requiring large amounts of metabolic activity to power active transport mechanisms. This study uses a thermodynamic analysi...
Theoretical Biology and Medical Modelling 2017 14:2
Published on: 26 January 2017
Research
The progression of Human Immunodeficiency Virus (HIV) within host includes typical stages and the Antiretroviral Therapy (ART) is shown to be effective in slowing down this progression. There are great challen...
Theoretical Biology and Medical Modelling 2017 14:1
Published on: 18 January 2017
Research
Florida State has reported autochthonous transmission of Zika virus since late July 2016. Here we assessed the transmissibility associated with the outbreak and generated a short-term forecast.
Theoretical Biology and Medical Modelling 2016 13:20
Published on: 9 November 2016
Research
Epidemic models are being extensively used to understand the main pathways of spread of infectious diseases, and thus to assess control methods. Schools are well known to represent hot spots for epidemic sprea...
Theoretical Biology and Medical Modelling 2016 13:19
Published on: 12 October 2016
Erratum
Theoretical Biology and Medical Modelling 2016 13:18
Published on: 8 September 2016
The original article was published in Theoretical Biology and Medical Modelling 2014 11:1
Research
An artificial neural network approach was chosen to model the outcome of the complex signaling pathways in the gastro-intestinal tract and other peripheral organs that eventually produce the satiety feeling in...
Theoretical Biology and Medical Modelling 2016 13:17
Published on: 7 July 2016
Review
Coordinated interaction of single cells by cell-to-cell communication (signalling) enables complex behaviour necessary for the functioning of multicellular organisms. A quite newly discovered cell-to-cell sign...
Theoretical Biology and Medical Modelling 2016 13:16
Published on: 6 June 2016
Research
In mathematical epidemiology, age-structured epidemic models have usually been formulated as the boundary-value problems of the partial differential equations. On the other hand, in engineering, the backsteppi...
Theoretical Biology and Medical Modelling 2016 13:15
Published on: 10 May 2016
Research
One common observation in infectious diseases caused by multi-strain pathogens is that both the incidence of all infections and the relative fraction of infection with each strain oscillate with time (i.e., so...
Theoretical Biology and Medical Modelling 2016 13:14
Published on: 18 April 2016
Research
This study is mainly motivated by the need of understanding how the diffusion behavior of a biomolecule (or even of a larger object) is affected by other moving macromolecules, organelles, and so on, inside a ...
Theoretical Biology and Medical Modelling 2016 13:13
Published on: 14 April 2016
Research
Dengue is a common mosquito-borne viral disease epidemic especially in tropical and sub-tropical regions where water sanitation is not substantially controlled. However, dengue epidemics sometimes occur in non...
Theoretical Biology and Medical Modelling 2016 13:12
Published on: 12 April 2016
Review
The cell state splitter is a membraneless organelle at the apical end of each epithelial cell in a developing embryo. It consists of a microfilament ring and an intermediate filament ring subtending a microtub...
Theoretical Biology and Medical Modelling 2016 13:11
Published on: 10 March 2016
Research
In recent epidemiological models, immunity is incorporated as a simplified value that determines the capacity of an individual to become infected or to transmit the disease. Moreover, the quality of the immune...
Theoretical Biology and Medical Modelling 2016 13:10
Published on: 5 March 2016
